Karame is a mummy-like creature that works for the Uruha Shishiten member, Kadotsu. Karame possesses a Shikigami, has the power to control paper. He is defeated by Fūko Kirisawa, who states that he lacked Saicho's grace.
After Fuko leaves to pursue Kirito, who had taken the disk back, Domon encounters Karame. Seeing that Fuko had left after beating up Karame, Domon moves on and throws Karame back down into the ground. What happens to Karame afterwards is unknown.